Fig. 2

Variant calling assessment. a Total computational cost (SUs) of calling variants on chromosome 21 in varying group sizes. Adjusted R2 provided for linear (purple) and quadratic (green) fits. b Computational cost per sample (relative to individual variant calling approach) of calling variants on chromosome 21 in varying group sizes. Adjusted R2 provided, assuming linear (purple) and quadratic (green) fits for total computational cost. c, d Sensitivity c and specificity d of variant calls on NA12878 versus estimated proportion of European admixture within a group (normalized by chromosome). e Admixture estimates of groups used for variant calling