Phylodynamic reconstruction of the spatiotemporal transmission and demographic history of coxsackievirus B2

BMC Bioinformatics

Table 2 Summary statistics used in tests of demographic neutrality and tree balance

Gene region	Statistical measures	Mean	Median	95 % HPD^a
VP1	D ^b	-2.9149	-2.933	-3.5863, -2.1837
	B ₁ ^c	24.9094	24.9591	22.9639, 26.9044
	Cn ^d	15.7291	16	14, 18
	Ic ^d	0.1969	0.1902	0.1682, 0.2384
3D	D	-2.1294	-2.1457	-2.818, -1.4114
	B ₁	16.7549	16.6385	15.5468, 18.0199
	Cn	11.0685	11	10, 12
	Ic	0.238	0.2386	0.1875, 0.2822

^aHPD Highest posterior density
^b D Fu and Li’s D: Normalized difference between the external branch lengths and total tree length. This is a classic summary statistic used for testing neutrality
^c B ₁ Maximum number of nodes between an internal node and the tips of the tree. A larger value indicates a more balanced tree
^d Cn Cherry count, the number of internal nodes with exactly two terminal branches. A larger number indicates a more balanced tree
^e Ic Colless’s tree imbalance index with a range of [0, 1]. A larger number indicates a more imbalanced tree

ISSN: 1471-2105