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Table 1 Performance of different cleaning approaches when there is no genuine correlation between genes (based on 1000 simulation runs)

From: Systematic noise degrades gene co-expression signals but can be corrected

Method

Raw

BC

BC+QN

RUV-random

FN2

0.126

0.124

0.125

0.001

  1. The performance was measured using a measure similar to the squared Frobenius norm (FN2) measure (explained in the text), which should be close to 0. All parameter choices and details of the simulation can be found in Additional file 1. All standard deviations were <0.001
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BMC Bioinformatics

ISSN: 1471-2105

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