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Table 3 Performance of RUV-random for different average absolute value of gene-gene correlations (based on 1000 simulation runs)

From: Systematic noise degrades gene co-expression signals but can be corrected

Average gene-gene correlation

% WS

FN2

0.2586

2.0

0.006

0.2905

1.4

0.005

0.3384

0.9

0.004

0.4225

0.5

0.008

  1. The performance was measured using the percentage of estimates with the wrong sign (WS). While FN2 refers to a squared Frobenius norm (FN2) measure (explained in the text), which should be close to 0. All parameter choices and details of the simulation can be found in Additional file 1. All standard deviations for FN2 were <0.001
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BMC Bioinformatics

ISSN: 1471-2105

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