Fig. 6
From: DECIPHER: harnessing local sequence context to improve protein multiple sequence alignment
Average execution time according to the number of sequences being aligned (note the axis breaks and log-scale). PROMALS [27] was substantially slower than the other programs that do not rely on a large external database of sequences. MAFFT [49] was the fastest program for large sequence sets. PASTA was the slowest program tested for aligning large sequence sets, requiring an average of 2.7Â h to align 4,000 sequences. A noteworthy speed improvement was obtained with DECIPHER by using multiple processors