Fig. 2

Regulator coupling property. If the transcription factors j and j ^′ are co-expressed (\(\phantom {\dot {i}\!}\omega _{j,j^{\prime }}\) is high, represented by a solid edge), and there exists at least one gene k that is not a TF, and is co-regulated by both j and j ^′, then the presence in the inferred graph of edge e _i,j is coupled with the presence of \(e_{i,j^{\prime }}\phantom {\dot {i}\!}\)