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Fig. 8 | BMC Bioinformatics

Fig. 8

From: Sequence specificity between interacting and non-interacting homologs identifies interface residues – a homodimer and monomer use case

Fig. 8

Exploring performance of different e-value cut-offs. a Average AUC with increasing HSP length. Each line represents a choice of setting the e-value threshold to define pair groups. 'Mixed' means pair groups mixed in at most 20 % monomer sequences to the interacting sub-group and at most 20 % homodimers to monomer sub-group (20 % homodimers, 80 % monomers); 'the lower e-value' represent using the lower e-value of the two (as described in the main text) as the same cut-off to separate H/M and M/H to form new groups. b Same as a with minimal sequence length 400. Performance seems insensitive to the threshold scheme chosen, but 'Mixed' performs slightly worse than the other three

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BMC Bioinformatics

ISSN: 1471-2105

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