Fig. 2

Exemplary comparison of four DNA motifs of length one using the Jensen-Shannon divergence. Motif 1 and motif 2 are depicted as sequence logos. For each column, we compare the motif in the first row with the motif in the second row using the Jensen-Shannon divergence listed in the third row. In the first example we depict the case with only one base in each motif resulting in a maximal Jensen-Shannon divergence of 1 bit. In the second example we depict the case with two equally abundant bases both in motif 1 and motif 2 (both different) resulting again in a maximal Jensen-Shannon divergence of 1 bit. In the third example we depict the case with two equally abundant bases both in motif 1 and motif 2 (one equal and one different) resulting in a Jensen-Shannon divergence of 0.5 bit. In the fourth example we depict the case with two bases both in motif 1 and motif 2 (differentially abundant) resulting in a Jensen-Shannon divergence of 0.25 bit