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Table 2 Conserved motifs of the GmrSD proteins

From: Phylogenomics and sequence-structure-function relationships in the GmrSD family of Type IV restriction enzymes

Domain Described motif Homologous motif of known function (protein) Predicted function
GmrS QR Conserved residues present in the DGQHR domain, unknown function No function prediction
GmrS I/VDGQQR FG/SGCHR – signature sequence of sulfiredoxins NTP binding, endonuclease
GmrS FxxxN Conserved residues present in the DGQHR domain, unknown function No function prediction
GmrD E/D-H-N-N D-H-N-N in HNH endonuclease from G. metallireducens, E-H-N-N in the periplasmic nuclease Vvn Endonuclease