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Fig. 2 | BMC Bioinformatics

Fig. 2

From: Fully automated registration of vibrational microspectroscopic images in histologically stained tissue sections

Fig. 2

Index color images acquired by k-means clustering. a Index image of the spectral image using k=8; (b) index image part of the corresponding area in the stained image using k=10. Black color corresponds to background; the cyan square in the spectral image is caused by a measurement artifact. Obviously, no one-to-one correspondence between the color indices of the two images exists. The mutual information of these two images is 0.5145, while the entropies of two images are 3.1196 and 2.9664, respectively. Note the background segmentation is not perfect, e.g. in the spectral image, the orange segment should be identified as background

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