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Fig. 6 | BMC Bioinformatics

Fig. 6

From: Fully automated registration of vibrational microspectroscopic images in histologically stained tissue sections

Fig. 6

Registration result of different methods for a single tissue microarray spot. The spot diameter is roughly 1.5 mm, and registration fails for both MS/gradient and MS/evo, but works successfully for our newly proposed Binary RMI/sparse and RMI/sparse. Results on all 56 TMA spots are summarized in the text and detailed in Additional file 3. In the first row of columns 3–6, green indicates foreground area in the FTIR image and purple indicates foreground area in the H&E image, so that white areas indicate foreground overlap between the registered images

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