Fig. 1
From: A new network representation of the metabolism to detect chemical transformation modules
Reaction network to Reaction Molecular Signature network. This figure presents a toy example of the reduction of a reaction network in a RMS network. Reactions sharing a same reaction signature (same node color in the figure) are grouped in a single RMS node. Directed edges of the reaction network are also merged in the RMS network. Red edges illustrate the computation of Markov transition probabilities P r(R M S 2∣R M S 1), P r(R M S 3∣R M S 1) and P r(R M S 5∣R M S 1). They correspond to the proportion of reaction edges, among the five outgoing edges of RMS1 reactions (blue nodes), connecting RMS1 to RMS2, RMS3 and RMS5