Table 4 Results for the set of computational methods considered for each TF of the Homo sapiens organism. The ν _auc is defined through the mean and variance of the A U C _N using a cross-validation method. Given a TF and method, ν _auc is chosen with maximum mean and lower variance in the A U C _N

ELK4

0.99923

0.99993

1

1

0.99961

1

0.99566

ETS1

0.98621

0.98845

0.99707

0.98533

0.99473

0.99508

0.99415

NFATC2

0.98291

0.98915

0.97952

0.97091

0.94311

0.98284

0.98263

MYCMAX

0.9951

0.98872

0.98823

0.98187

0.96281

0.99178

0.98581

E2F1

0.99991

0.99963

1

0.99915

0.99685

0.99958

0.99566

MAX

0.99968

0.99743

1

0.99741

0.99275

0.99852

0.98583

NFIL3

0.9992

0.9994

0.99256

0.99558

0.999823

0.99917

0.98408

NFE2L2

0.98975

0.93901

0.98573

0.94418

0.96973

0.99974

0.9845

INSM1

0.99993

0.99891

1

0.99741

0.9906

0.99842

0.98885

CREB1

0.99965

0.99763

1

0.99793

0.99962

0.99953

0.99567

Irf2

0.99995

1

1

1

0.99773

0.99995

0.98817

FOXO3

0.99638

0.99817

1

0.99688

0.95549

0.98567

0.9915

HLF

0.99943

0.99343

1

0.99155

0.98706

0.99113

0.99216

NFkappaB

0.99987

1

1

1

0.98657

0.98256

0.98217

MZF114

0.99387

0.97925

1

0.97751

0.98682

0.98743

0.98775

ESR1

0.99962

0.99901

1

0.99725

0.98974

0.98903

0.9957

FOXD1

0.99814

0.99436

1

0.99043

0.99549

0.99787

0.99133

MZF1513

0.99719

0.97549

1

0.98534

0.9833

0.98193

0.98585

Ap1

0.98465

0.97231

1

0.97121

0.95825

0.97469

0.99445