Table 6 The level of significance corresponding to −l o g ₁₀ (p _value ) calculated using the Wilcoxon-rank test for the Homo sapiens organism. The null hypothesis is that the AUC distributions between SIGMA and the other computational methods are the same and the alternative hypothesis is that the AUC distributions are different. p _value >0.05 is in shown in bold

ELK4

1.58

1.46

5.80

9.41

9.48

9.60

ETS1

3.48

7.55

7.96

7.52

7.51

7.85

NFATC2

0.71

7.61

2.81

5.21

9.48

9.59

MYCMAX

2.25

7.59

2.31

7.83

7.55

9.60

E2F1

1.58

7.12

2.33

3.12

7.56

9.6

MAX

3.73

4.16

2.66

5.13

5.10

6.46

NFIL3

1.20

6.10

1.19

6.05

6.21

7.82

NFE2L2

1.20

4.10

0.80

2.98

4.35

5.11

INSM1

2.33

8.63

1.20

2.08

8.95

10.11

CREB1

2.31

8.47

1.20

1.20

8.47

8.68

Irf2

0.80

6.79

3.37

6.14

6.78

6.89

FOXO3

2.31

6.11

5.63

5.20

6.48

8.26

HLF

3.38

4.45

0.80

1.20

2.08

6.02

NFkappaB

1.20

6.87

3.40

6.50

6.83

6.96

MZF114

7.52

13.95

10.99

3.90

14.11

9.65

ESR1

1.95

6.10

3.74

5.43

6.11

7.81

FOXD1

1.95

1.32

1.20

1.09

7.11

8.22

MZF1513

6.10

3.72

3.41

3.78

3.71

4.32

Ap1

4.75

13.51

2.67

3.03

13.5

17.14