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Fig. 8 | BMC Bioinformatics

Fig. 8

From: AlignWise: a tool for identifying protein-coding sequence and correcting frame-shifts

Fig. 8

Comparing FSCs made by AlignFS, Genewise and AlignWise in human cDNAs and newt transcripts. a, b and c) Show results from the human cDNAs, using the RefSeq database, as shown in Table 3 and Fig. 6. d, e and f Show results from the newt transcripts. a Venn diagram of the number of FSCs made by AlignFS and Genewise. b The number of perfect FSCs made by AlignFS and Genewise. c Venn diagram of the number of incorrect FSCs made by AlignFS and Genewise. d Venn diagram of the number of FSCs made by AlignFS and Genewise intersecting with the putative frame-shifts identified previously [7]. e Illustrates the decisions made by AlignWIse for each of the 5,652 sequences that Genewise made FSCs in. Identical (yellow): Genewise and AlignFS make identical FSCs, Genewise (green): The Genewise FSC is selected, AlignFS(FSC)(blue): The AlignFS FSC is selected, AlignFS(NC)(red): The uncorrected AlignFS sequence is used.f For the proteins in (e), the percent identity against the original top BLASTx hit is compared for AlignFS and Genewise. Colours as in (e)

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