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Table 5 A summary of ORF finding programs

From: AlignWise: a tool for identifying protein-coding sequence and correcting frame-shifts

Program

Finds ORFs

Outputs DNA sequences

Able to correct frame-shifts

Accurate at short evolutionary distances

Accurate at long evolutionary distances

AlignWise

Y

Y

Y

Y

Y

AlignFS

Y

Y

Y

Y

N

Genewise

Y

Y

Y

N

Y

ESTscan

Y

Y

Y

N

N

TransDecoder

Y

Y

N

N/A

N/A

OrfPredictor

Y

Y

N

N/A

N/A

MACSE

Na

Y

Y

N/A

N/A

BLASTx

Y

N

N

N/A

N/A

ESTwise

Y

N

Y

N/A

N/A

  1. aWe have indicated that MACSE was unable to find ORFs as it was unable to complete any analysis within a reasonable time frame