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Fig. 7 | BMC Bioinformatics

Fig. 7

From: Analysis of in vivo single cell behavior by high throughput, human-in-the-loop segmentation of three-dimensional images

Fig. 7

Differences in cell phase indices along the medial-lateral axis of the mouse olfactory epithelium. a Left: A transverse vibratome section of an E9.5 embryo including the two olfactory placodes (yellow box). Right: High magnification image of the placodes stained for DNA (cyan) and EdU (green). Placodes were divided into “center” and “outer ring” regions for analysis. b DNA content histograms of EdU+ (red) and EdU− (blue) cells in center and outer ring regions. c During cell detection, M-phase cells in the process of cytokinesis were segmented as two separate cells and were annotated as being a “half cell”. Conversely, M-phase cells before cytokinesis were annotated as being a “full cell”. DNA content histograms of “half” (magenta) and “full” (green) cells are appropriately centered at 2C and 4C, respectively

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BMC Bioinformatics

ISSN: 1471-2105

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