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Fig. 1 | BMC Bioinformatics

Fig. 1

From: An affinity-structure database of helix-turn-helix: DNA complexes with a universal coordinate system

Fig. 1

Database creation steps. Protein-DNA structures and position weight matrices (PWMs) were first curated from existing databases and the primary literature. Newly developed structural alignments algorithms were then used to establish a correspondence between structures and PWMs, by associating a probability distribution with every residue in every protein-DNA structural complex. Finally the resulting structures were clustered and aligned to establish a universal coordinate system across all helix-turn-helix domains

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