TY - JOUR AU - Yazdani, Akram AU - Yazdani, Azam AU - Boerwinkle, Eric PY - 2015 DA - 2015/12/04 TI - Rare variants analysis using penalization methods for whole genome sequence data JO - BMC Bioinformatics SP - 405 VL - 16 IS - 1 AB - Availability of affordable and accessible whole genome sequencing for biomedical applications poses a number of statistical challenges and opportunities, particularly related to the analysis of rare variants and sparseness of the data. Although efforts have been devoted to address these challenges, the performance of statistical methods for rare variants analysis still needs further consideration. SN - 1471-2105 UR - https://doi.org/10.1186/s12859-015-0825-4 DO - 10.1186/s12859-015-0825-4 ID - Yazdani2015 ER -