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Fig. 3 | BMC Bioinformatics

Fig. 3

From: PC-TraFF: identification of potentially collaborating transcription factors using pointwise mutual information

Fig. 3

PC-TraFF significant collaborating TFBS pairs based on breast cancer-associated promoter sequences of human RefSeq genes. Blue lines denote interactions between TFs whose importance is experimentally verified whereas red lines indicate potential interactions between transcription factors that have not been experimentally validated yet. The binding sites V$NFKB_Q6, V$CETS1P54_01, and V$MYCMAX_B constitute three hubs in the predicted collaboration network of significant TFBS pairs. The hubs and their top three collaboration partners are given in Table 9

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BMC Bioinformatics

ISSN: 1471-2105

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