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Fig. 1 | BMC Bioinformatics

Fig. 1

From: Bioinformatics approach to predict target genes for dysregulated microRNAs in hepatocellular carcinoma: study on a chemically-induced HCC mouse model

Fig. 1

Progressive liver damage induced by DEN. a-b) Livers from mice sacrificed at 6 (a) and 11 months (b). Dark arrows indicate nodular structures visible on liver’s surface. c) H&E staining showing normal hepatic parenchyma (L lobe, original magnification 10X) from a control mouse sacrificed after 3 months. d-e) Mouse hepatic tissues (L lobe) from 3- (D, original magnification 10X) and 6-months (E, original magnification 40X) DEN-treated mice. Dashed circle and arrows indicate the presence of infiltrating lymphocytes and cellular atypia. f) Liver parenchyma from an 11-months DEN-treated mouse (L lobe, original magnification 10X). Marked hyperaemia, micronodules and high density of perisinusoidal lymphocytes are detected

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BMC Bioinformatics

ISSN: 1471-2105

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