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Fig. 2 | BMC Bioinformatics

Fig. 2

From: Bioinformatics approach to predict target genes for dysregulated microRNAs in hepatocellular carcinoma: study on a chemically-induced HCC mouse model

Fig. 2

Workflow of the miRNA analysis. MiR-125a-5p, miR-27a, miR-193b and miR-182 have been considered in our analysis. We look for their common targets on four on-line DB (microrna.org, Targetscan.org, PITA and Rna-22) in order to obtain four predicted targets lists, one for each DB. From these lists, only 15 targets have been considered. We gave the filtered list of targets as input to GENEMANIA in order to obtain a physical relation network. Finally, we built up a network showing the relationships between miRNAs and targets, as well as those among targets by using Neo4j

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BMC Bioinformatics

ISSN: 1471-2105

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