Bioinformatics approach to predict target genes for dysregulated microRNAs in hepatocellular carcinoma: study on a chemically-induced HCC mouse model

Table 1 Relative expression of miRNAs considered for the analysis in livers and tumors

	RQ 3 M	RQ 6 M	RQ 11 M	RQ 11 M	RQ 11 M
	(DEN/CTR)	(DEN/CTR)	(DEN/CTR)	(DEN-T/CTR)	(DEN-T/DEN)
125 a-5p	0,75	0,92	2,2	3,34	1,52
182	0,97	1,05	3,52	10,09	2,86
193 b	1	1,65	1,33	4,89	3,67
27 a	0,17	15,72	4,27	4,89	1,11

RQ value is the relative quantification of miRNA expression, depending on the treatment’s length (3, 6, 11 months), obtained by comparing hepatic samples from DEN-treated (DEN), controls (CTR), and tumor samples (DEN-T) from DEN-treated mice, as indicated in the round brackets. Results are mean of 3 iterations

ISSN: 1471-2105