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Table 3 The common pathways by using DAVID and CPDB for early-stage NSCLC (the p M -value and p T -value represent the corresponding p-value obtained by machine learning algorithms and topological parameter-based classification)

From: Drug repositioning for non-small cell lung cancer by using machine learning algorithms and topological graph theory

DAVID

KEGG

REACTOME

pathname

p M -value

p T -value

pathname

p M -value

p T -value

NULL

  

NULL

  

CPDB

KEGG

REACTOME

pathname

p M -value

p T -value

pathname

p M -value

p T -value

Endocytosis

0.01340

0.00045

Cell-Cell communication

0.02810

0.00432

Glycolysis/Gluconeogenesis

0.02330

0.00249

Glucose metabolism

0.02420

0.02000

Hematopoietic cell lineage

0.04060

0.03380

Regulation of PLK1 Activity at G2/M Transition

0.03700

0.03070

Gap junction

0.04700

0.03930

Metabolism of nucleotides

0.03940

0.03280

   

Cell junction organization

0.00765

0.03590

   

Platelet activation, signaling and aggregation

0.04720

0.03630