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Table 7 IC50 values of potential drugs for early-stage NSCLC

From: Drug repositioning for non-small cell lung cancer by using machine learning algorithms and topological graph theory

Machine learning algorithms

 cMap drug name

MTT (μM)

Clonogenic (μM)

  mebendazole

<1

 

  vorinostat

<1

 

  pyrvinium

<0.1

 

  niclosamide

>5

 

  nortriptyline

 

<10

  piperlongumine

>5

 

  trichostatin A

  

  trioxysalen

>5

 

Topological parameter-based classification

 cMap drug name

MTT (μM)

Clonogenic (μM)

  trichostatin A

<1

 

  vorinostat

<1

 
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BMC Bioinformatics

ISSN: 1471-2105

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