From: Gene expression profiling identifies candidate biomarkers for active and latent tuberculosis
TB vs. HC | LTBI vs. HC | LTBI vs. TB |
---|---|---|
1. Immune response | Regulation of metabolic process | Response to cold |
2. Leukocyte differentiation | Regulation of cellular Metabolic process | Immune Response-regulating signaling pathway |
3. Immune system process | Regulation of biosynthetic process | Cellular process |
4. B cell activation | Apoptotic process | Immune response- activating signal transduction |
5. Lymphocyte differentiation | Death | Heterotypic cell-cell adhesion |
6. Regulation of immune response | Regulation of gene expression | NK T cell differentiation |
7. Positive regulation of response to stimulus | MAP kinase phosphatase activity | Regulation of mRNA catabolic process |
8. Lymphocyte activation | Translation factor activity, | Translation regulator activity |
9. Leukocyte activation | Translation initiation factor activity | NF-kappaB binding |
10. Chemokine receptor activity | Protein tyrosine/threonine phosphatase activity | Translation repressor activity |