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Table 2 FNA performance per cytology group

From: The diagnostic application of RNA sequencing in patients with thyroid cancer: an analysis of 851 variants and 133 fusions in 524 genes

Performance on Cytology Benign (n = 30)

Genetic alteration

Histology malignant (n = 6)

Histology benign (n = 24)

Positive

0

4

Negative

6

20

  1. Sensitivity, 0 % (0–46); Specificity, 83 % (63–95); PPV, 16 % (5–50); NPV, 79 % (73–85), prevalence of malignant lesions, 20 %. Estimated performance when malignancy is prevalent at 6 %: PPV, 5 % (1–20); NPV, 94 % (91–96)
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BMC Bioinformatics

ISSN: 1471-2105

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