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Table 4 FNA performance per cytology group

From: The diagnostic application of RNA sequencing in patients with thyroid cancer: an analysis of 851 variants and 133 fusions in 524 genes

Performance on FN/SFN (n = 10)

Genetic alteration

Histology malignant (n = 2)

Histology benign (n = 8)

Positive

1

2

Negative

1

6

  1. Sensitivity, 50 % (1–99); Specificity, 75 % (35–97); PPV, 33 % (7–76); NPV, 86 % (59–96), prevalence of malignant lesions, 20 %. Estimated performance when malignancy is prevalent at 24 %: PPV, 39 % (9–80); NPV, 83 % (53–95)
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BMC Bioinformatics

ISSN: 1471-2105

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