Fig. 4

Artificial differential network of genetic interactions. A comparison of Diffany results with a previously published (artificial) differential network involving positive (alleviating) and negative (aggrevating) genetic interactions. a: The original picture by [6]. The reference network is denoted as ‘Condition 1’ and the condition-specific network as ‘Condition 2’. The differential network is displayed at the right, and the consensus network at the bottom (‘Housekeeping interactions’). b-e: The differential d and consensus networks e produced by Diffany from the same input data. Because they do not contribute to an enhanced understanding of the molecular rewiring, unconnected nodes are not included in the networks