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Table 1 Mendelian error rate (Simulation II). The mean number of Mendelian errors for each offspring with sequencing coverage of 5x, 10x. 20x and 30x from our proposed method “FamLDCaller” (FLDC) compared with the results from Genome Analysis Toolkit (GATK). (F3: trios; F4: nuclear families of two offspring; F5: nuclear families with three offspring and F6: complex families with three generations.)

From: A computational method for genotype calling in family-based sequencing data

Depth 5 10 20 30
Method GATK FLDC GATK FLDC GATK FLDC GATK FLDC
F3 28,213 1118 6475 483 927 182 628 164
F4 28,213 962 6475 350 927 135 628 126
F5 28,213 718 6475 228 927 94 628 86
F6 33,427 351 7420 99 1161 46 805 39