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Table 5 Top five predicted interactions by KRONRLS-MKL

From: A multiple kernel learning algorithm for drug-target interaction prediction

Drug Target  
Nuclear Receptors  
D00951 Medroxyprogesterone acetate hsa2099 estrogen receptor 1 (D,C)
D00585 Mifepristone hsa2099 estrogen receptor 1 (C)
D00182 Norethisterone hsa2099 estrogen receptor 1 (C)
D00105 Estradiol hsa5241 progesterone receptor (C)
D00094 Tretinoin hsa6095 RAR-related orphan receptor A  
D02358 Metoprolol hsa154 adrenoceptor beta 2, surface (D,C)
D00283 Clozapine hsa1814 dopamine receptor D3 (D,C,M)
D00371 Theophylline hsa135 adenosine A2a receptor (K,D,C)
D00371 Theophylline hsa134 adenosine A1 receptor (K,D,C)
D00095 Adrenaline hsa155 adrenoceptor beta 3 (K,D,C)
Ion Channel  
D00775 Riluzole hsa2898 glutamate receptor, ionotropic, kainate 2 (M)
D02356 Verapamil hsa6833 ATP-binding cassette, sub-family C (CFTR  
D00294 Diazoxide hsa10060 ATP-binding cassette, sub-family C (CFTR  
D02356 Verapamil hsa56660 potassium channel, two pore domain subfamily K, member 12  
D00524 Carbachol hsa1134 cholinergic receptor, nicotinic, alpha 1 (muscle)  
D00542 Halothane hsa1571 cytochrome P450, family 2, subfamily E, polypeptide 1 (D,C,M)
D00437 Nifedipine hsa1559 cytochrome P450, family 2, subfamily C, polypeptide 9 (D,C,M)
D00528 Anhydrous caffeine hsa1549 cytochrome P450, family 2, subfamily A, polypeptide 7 (M)
D03670 Deferoxamine hsa1579 cytochrome P450, family 4, subfamily A, polypeptide 11  
D00139 Methoxsalen hsa1543 cytochrome P450, family 1, subfamily A, polypeptide 1 (D,M)
  1. Interactions found in KEGG, DrugBank, ChEMBL and Matador are marked as K, D, C and M respectively