Table 15 The 34 tumor related genes selected by RS on original training group of Cancers dataset
From: Informative gene selection and the direct classification of tumors based on relative simplicity
Symbol | Synonym(s) | Entrez Gene Name | Related carcinoma and Ref. |
|---|---|---|---|
CYP1A1 | AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 | lung cancer [45] |
PTPRZ1 | HPTPZ, HPTPzeta, PTP-ZETA, PTP18, PTPRZ, PTPZ, R-PTP-zeta-2, RPTPB, RPTPbeta, phosphacan | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | lung cancer [46] |
WT1 | AWT1, EWS-WT1, GUD, NPHS4,WAGR, WIT-2, WT33 | Wilms tumor 1 | leukemic [47] |
ANGPT2 | AGPT2, ANG2 | angiopoietin 2 | lung cancer [48] |
LGALS1 | GAL1, GBP | lectin, galactoside-binding, soluble, 1 | hepatocellular carcinoma [49] |
ACPP | 5'-NT, ACP-3, ACP3 | acid phosphatase, prostate | prostate cancer [50] |
GC | DBP, DBP/GC, GRD3, HEL-S-51, VDBG, VDBP | group-specific component (vitamin D binding protein) | bladder cancer [51] |
PRMT1 | ANM1, HCP1,HRMT1L2, IR1B4 | protein arginine methyltransferase 1 | breast cancer [52] |
NOX1 | GP91-2, MOX1, NOH-1, NOH1 | NADPH oxidase 1 | colon cancer [53] |
ADH7 | ADH4 | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide | gastric cancer [54] |
DSG3 | CDHF6, PVA | desmoglein 3 | bladder carcinoma [55] |
NKX2-1 | BCH, BHC, NK-2, NKX2.1, NKX2A, T/EBP, TEBP, TITF1, TTF-1, TTF1 | NK2 homeobox 1 | lung cancer [56] |
EFHD1 | MST133, MSTP133, PP3051, SWS2 | EF-hand domain family, member D1 | colorectal cancer [57] |
EREG | EPR, ER, Ep | epiregulin | colorectal cancer [58] |
DHRS2 | HEP27, SDR25C1 | dehydrogenase/reductase (SDR family) member 2 | breast cancer [59] |
ENPEP | APA, CD249, gp160 | glutamyl aminopeptidase (aminopeptidase A) | prostate cancer [60] |
SCGB2A2 | MGB1, UGB2 | secretoglobin, family 2A, member 2 | breast cancer [61] |
KRT13 | CK13, K13, WSN2 | keratin 13, type I | breast cancer [62] |
SERPINC1 | AT3, AT3D, ATIII, THPH7 | serpin peptidase inhibitor, clade C (antithrombin), member 1 | bladder cancer [63] |
SLC12A2 | BSC, BSC2, NKCC1, PPP1R141 | solute carrier family 12 (sodium/ potassium/chloride transporter),member 2 | esophageal squamous cell carcinoma [64] |
IRF4 | LSIRF, MUM1, NF-EM5, SHEP8 | interferon regulatory factor 4 | hematological malignancies [65] |
GPA33 | A33 | glycoprotein A33 (transmembrane) | colorectal cancer [66] |
BCAT1 | BCATC, BCT1, ECA39, MECA39, PNAS121, PP18 | branched chain amino-acid transaminase 1, cytosolic | colorectal cancer [67] |
COL10A1 | collagen, type X, alpha 1 | breast cancer [68] | |
CEL | BAL, BSDL, BSSLL, CEase, FAP, FAPP, LIPA, MODY8, CEL | carboxyl ester lipase | pancreatic cysts [69] |
NPC2 | EDDM1, HE1 | Niemann-Pick disease, type C2 | liver cancer [70] |
CDH17 | CDH16, HPT-1, HPT1 | cadherin 17, LI cadherin (liver-intestine) | gastric cancer [71] |
MEIS1 | Meis homeobox 1 | pancreatic cancer [72] | |
KLK3 | APS, KLK2A1, PSA, hK3 | kallikrein-related peptidase 3 | prostrate [73] |
CXCL13 | ANGIE, ANGIE2, BCA-1, BCA1, BLC, BLR1L, SCYB13 | chemokine (C-X-C motif) ligand 13 | breast cancer [74] |
ELA3A | ELA3,ELA3A | chymotrypsin-like elastase family, member 3A | pancreatic carcinoma [75] |
IRX5 | HMMS, IRX-2a, IRXB2 | iroquois homeobox 5 | prostate cancer [76] |
VCAM1 | CD106, INCAM-100 | vascular cell adhesion molecule 1 | ovarian cancer [77] |
P4HB | CLCRP1, DSI, ERBA2L, GIT, P4Hbeta, PDI, PDIA1, PHDB, PO4DB, PO4HB, PROHB | prolyl 4-hydroxylase, beta polypeptide | Glioblastoma multiforme [78] |