Fig. 6
From: Fast, accurate, and lightweight analysis of BS-treated reads with ERNE 2
Time of alignment and methylation calling required by ERNE-BS 2 with ERNE-METH 2 and Bismark (Bowtie 1/Bowtie 2) with bismark_methylation_extractor. The ERNE 2 pipeline is from 1.6 to 3.6 times faster than the Bismark pipeline (using Bowtie 1/Bowtie 2, respectively). BSMAP is not shown here since its methylation caller required too much RAM (26 GB) to be run on our system