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Fig. 2 | BMC Bioinformatics

Fig. 2

From: Measure transcript integrity using RNA-seq data

Fig. 2

Evaluating median TIN score (medTIN) and RIN metric using sample level average RNA fragment size. The average RNA fragment size of a sample was estimated from all read pairs that uniquely mapped to the reference genome (see Methods). a Correlation between RIN score and the average RNA fragment size for 12 GMB samples. b Correlation between medTIN and average RNA fragment size for 12 GMB samples. c Correlation between RIN score and average RNA fragment size for 120 mCRPC samples. d Correlation between medTIN and average RNA fragment size for 120 mCRPC samples. (c-d) Samples with RIN < 3 and RIN ≥3 were indicated as red and blue circles, respectively. (a-d) Linear regression lines fitted to data are indicated as black dashed lines

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