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Fig. 5 | BMC Bioinformatics

Fig. 5

From: Analysing multiple types of molecular profiles simultaneously: connecting the needles in the haystack

Fig. 5

Comparing individual and joint tests: overlap and dilution. Top row: overlap between individual and joint tests. Computed as the proportion of genes selected by both its expression being associated with the joint set of covariates, formed by both copy number and expression, as well as by each single set of covariates, per chromosome arm. This proportion is relative to all selected joint tests. Bottom row: dilution. Computed as the proportion of selected genes for expression association with one set of covariates (either copy number or methylation), that are not selected with the joint set of covariates, formed by both copy number and expression, per chromosome arm. The proportion is relative to all selected tests for association with either copy number (bottom-left) or methylation (bottom-right)

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