Fig. 4
From: Intra- and interspecies gene expression models for predicting drug response in canine osteosarcoma
Tumor-trained models on clinical outcome in canine osteosarcoma patients treated with doxorubicin and/or carboplatin. a & b Analysis comparing the survival curves of COS33 patients predicted to respond or not respond to doxorubicin (n = 22) (a) or carboplatin (n = 25) (b) from models where genes identified from the NCI60 panel were co-expressed and trained on the COS16 tumor panel. c & d Survival analysis of predicted responders and non-responders to doxorubicin (c) or carboplatin (d) of COS33 patients from models where genes identified from the FACC panel were co-expressed and trained on the COS16 tumor panel. Significant difference in disease free interval between predicted groups was determined by Log Rank test