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Fig. 2 | BMC Bioinformatics

Fig. 2

From: Analysis of secondary structural elements in human microRNA hairpin precursors

Fig. 2

Diagrams of bulge and internal loops that have the same motifs but different orientations in miRNA hairpin precursor secondary structure (ad), and a multibranch loop motif (e). (a) 5’ bulge loop (AU)U/-(GC), (b) 3’ bulge loop (CG)-/U(UA), (c) internal loop (CG)C/A(UA), (d) internal loop (AU)A/C(GC), and (e) multibranch loop (CG)A(GU)U(GC)C(GC). The motifs can be characterized by the identity of unpaired nucleotides (red letters) or the identity of unpaired nucleotides and closing base pairs (red and black letters). Note: (AU)U/-(GC) and (AU)-/U(GC) are different motifs. The equivalent 3’ bulge for the 5’ bulge (AU)U/- (GC) is (CG) -/U(UA)

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