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Table 3 The p-value represents the results of a one-sided binomial hypothesis test where H 0:p 0=p 1 and H a :p 0>p 1 where p 0 is the proportion of structures found that had a corresponding entry in OMIM when using the quaternary version of the method and p 1 is the proportion of structures with a corresponding entry in OMIM when using the tertiary version of the method

From: Leveraging protein quaternary structure to identify oncogenic driver mutations

  Quaternary only Tertiary only p-value
Method Num structures Num in OMIM Num structures Num in OMIM  
iPAC 56 42 (75 %) 33 8 (24 %) 4.49×10−6
GraphPAC 43 31 (72 %) 27 10 (37 %) 4.04×10−3
SpacePAC 21 11 (52 %) 15 5 (33 %) 0.214