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Table 4 The table shows the specificity (Sp), sensitivity (Sn), true positives (TP), true negatives (TN), false negatives (FN), false positives (FP) and area under the ROC and PRC curves (auROC/PRC) as well as the time needed for obtaining the best combination for all methods and the five studied chromosomes for TIS recognition

From: Stepwise approach for combining many sources of evidence for site-recognition in genomic sequences

Chromosome Objective Method Combination auROC auPRC G Sp Sn TP FN TN FP #models Time (s)
Chr. 1 - Std - 0.9473 0.0929 0.8430 0.9528 0.7458 1608 548 7,693,177 381,413 - -
  auROC Cons Sum 0.9820 0.1529 0.8893 0.9874 0.8010 1727 429 7,972,989 101,601 8 1555
  auPRC Cons Sum 0.9669 0.1859 0.8326 0.9859 0.7032 1516 640 7,960,941 113,649 29 3436
  G Cons Majority 0.9445 0.0074 0.9353 0.9599 0.9114 1965 191 7,750,802 323,788 2 572
Chr. 3 - Std - 0.9334 0.0831 0.8335 0.9584 0.7248 843 320 6,988,324 303,627 - -
  auROC Cons Sum 0.9761 0.1449 0.8458 0.9929 0.7206 838 325 7,240,060 51,891 8 1807
  auPRC Cons Sum 0.9596 0.1762 0.7891 0.9920 0.6277 730 433 7,233,286 58,665 33 3708
  G Cons Majority 0.9315 0.0049 0.9238 0.9664 0.8831 1027 136 7,046,822 245,129 2 696
Chr. 13 - Std - 0.9506 0.0844 0.8692 0.9479 0.7971 271 69 3,473,147 191,017 - -
  auROC Cons Sum 0.9778 0.1347 0.8429 0.9940 0.7147 243 97 3,642,333 21,831 7 1348
  auPRC Cons Sum 0.9692 0.1608 0.7924 0.9929 0.6324 215 125 3,638,155 26,009 28 3280
  G Cons Majority 0.9483 0.0038 0.9385 0.9630 0.9147 311 29 3,528,645 135,519 2 476
Chr. 19 - Std - 0.9456 0.1277 0.8727 0.9068 0.8398 1185 226 1,540,551 158,340 - -
  auROC Cons Sum 0.9716 0.1726 0.8876 0.9691 0.8129 1147 264 1,646,337 52,554 7 1510
  auPRC Cons Sum 0.9575 0.2048 0.8534 0.9657 0.7541 1064 347 1,640,628 58,263 27 3269
  G Cons Majority 0.9436 0.0181 0.9346 0.9555 0.9142 1290 121 1,623,271 75,620 2 473
Chr. 21 - Std - 0.9353 0.0726 0.8409 0.9415 0.7511 175 58 1,227,429 76,205 - -
  auROC Cons Sum 0.9809 0.1299 0.8612 0.9875 0.7511 175 58 1,287,377 16,257 8 1526
  auPRC Cons Sum 0.9670 0.1635 0.8201 0.9857 0.6824 159 74 1,284,991 18,643 31 3352
  G Cons Majority 0.9362 0.0043 0.9271 0.9582 0.8970 209 24 1,249,122 54,512 2 288
  1. The results of our method for the three different evaluation measures are shown in boldface