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Fig. 2 | BMC Bioinformatics

Fig. 2

From: pcaReduce: hierarchical clustering of single cell transcriptional profiles

Fig. 2

Method illustration using an autoencoder network. Clustering is applied to the data representation at each linear hidden layer. If there are K−1 linear hidden units, the data is projected into a subspace spanned by the top K−1 principal components. Consistency between the clusterings at each layer is maintained by enforcing a hierarchical constraint. a Graphical interpretation of an autoencoder network(s). b Corresponding hierarchical structure

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