Sample size calculation while controlling false discovery rate for differential expression analysis with RNA-sequencing experiments

Table 3 Comparison of sample size calculation methods, including the proposed method in this paper, Zhao et al.’s approach (RnaSeqSampleSize) and Wu et al.’s approach (PROPER).

Results determined by our method were based on parameters estimated at m=200. Power was evaluated based on the voom and limma pipeline for our method, while edgeR for RnaSeqSampleSize and PROPER. The computation time for each simulation was calculated on a MacAir laptop with 1.3 GHz i7 CPU and 4GB RAM

ISSN: 1471-2105