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Fig. 3 | BMC Bioinformatics

Fig. 3

From: CollapsABEL: an R library for detecting compound heterozygote alleles in genome-wide association studies

Fig. 3

Relationship between N, MAF, β and median p-value from the GCDH analysis and single SNP association analysis. SNP pairs with different MAFs are drawn from 1000-Genomes imputed Rotterdam Study microarray data. Sample sizes are fixed at 8000 or 11,000. Allele effect sizes β ranges from 0.5 to 1.5. Median p-values for SNPs from different MAF groups are distinguished using different colors. In total 2750 simulations are conducted

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BMC Bioinformatics

ISSN: 1471-2105

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