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Fig. 1 | BMC Bioinformatics

Fig. 1

From: Gene signature-based mapping of immunological systems and diseases

Fig. 1

Similarity matrix of immune cell type gene signatures from human and mouse. Seventy-eight immune cell type gene signatures (20 human and 58 mouse) were paired against each other. Similarity was calculated by Fisher’s exact test of overlapping genes for each pair. Gene signatures were positioned according to their common cell lineage. Color represents the –log (P value of Fisher’s exact test), with red color indicating high similarity, and blue color indicating less/no similarity. Solid line black boxes group the gene signatures from the same lineage in either human or mouse, while dotted line black boxes group those from the same lineage between human and mouse. HSC hematopoietic stem cell, GN granulocyte, MO monocyte

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