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Fig. 7 | BMC Bioinformatics

Fig. 7

From: Gene signature-based mapping of immunological systems and diseases

Fig. 7

Clustering of immune drug target gene sets vs. immune disease signatures. One-hundred-twenty-six immune drug target gene sets were paired against 155 immune disease signatures. Hierarchical clustering was performed based on the similarity that was calculated by Fisher’s exact test of the overlapping genes for each pair. (I) Heatmap shows the clustering of drug target gene sets (columns) vs. the disease signatures (rows). A, B lists the diseases that are represented by disease signatures showing similarity with drug target gene sets indicated by C1 and C2. Bottom bar chart indicates the number of linked diseases for each drug target shown in the same order as the above heatmap. (II) C1, C2 tables list the details of drug targets and their linked diseases for drug target gene set clusters shown in (I)

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