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Fig. 3 | BMC Bioinformatics

Fig. 3

From: UNDR ROVER - a fast and accurate variant caller for targeted DNA sequencing

Fig. 3

Runtime comparison of GATK, ROVER and UNDR ROVER. Total sequential computing time of the GATK pipeline, ROVER and UNDR ROVER (thorough, genotyping and fast) when applied to 95 Hi-Plex samples targeting PALB2 and XRCC2 with 60 primer-pairs in the PCR. The computing time for the GATK and ROVER pipelines are decomposed into alignment with Bowtie (blue), conversion of alignment file from SAM to BAM format (yellow), indexing and sorting of BAM file (grey), and variant calling (light red for GATK and green for ROVER). Computing times for UNDR ROVER are shown for both the thorough mode (brown) and the fast mode with SNV genotyping (orange), and the fast mode without SNV genotyping (purple)

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