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Table 4 Validations of top 50 predicted drug indications for AD and PD, ordered by ranking

From: DrugGenEx-Net: a novel computational platform for systems pharmacology and gene expression-based drug repurposing

Alzheimer’s Disease (AD) Reference for Validation Parkinson’s Disease (PD) Reference for Validation
Rasagiline Weinreb et al. Neurotherapeutics. (6)1:163–74. (2009) [70] Dextroamphetamine Parkes et al. J Neurol Neurosurg Psychiatry. 38(3):232–7 (1975) [83]
Interferons Grimaldi et al. J Neuroinflammation. 11:30 (2014) [71] Orphenadrine Bersani et al. Clin Neuropharmacol. 13(6):500–6 (1990) [84]
Calcium Woods et al. Adv Exp Med Biol. 740:1193–217 (2012) [72] Quinacrine Tariq et al. Brain Res Bull. 54(1):77–82 (2001) [85]
Dovitinib Li et al. Medical Hypotheses. (80)4:341–44. (2013) [73] Atomoxetine Weintraub et al. Neurology. 75(5):448–55 (2010) [86]
Somatropin Recombinant Ling et al. Growth Horm IGF Res. (17)4:336–41 (2007) [74]   
Aripiprazole De Deyn et al. Expert Opin. Pharmacother. (14)4:459–74 (2013) [75]   
Clozapine Tariot et al. Clin Geriatr Med. (17)2:359–76 (2001) [76]   
Quercetin Ansari et al. J Nutr Biochem. 20(4):269–75 (2009) [77]   
Flavopiridol Pallàs et al. Med Hypotheses. 64(1):120–3 (2005) [78]   
Sunitinib Grammas et al. J Alzheimers Dis. 40(3):619–30 (2014) [79]   
Risperidone Katz et al. Int J Geriatr Psychiatry. (60)2:107–15 (2007) [80]   
Genistein Valles et al. Brain Res. 1312:138–44 (2010) [81]   
Dasatinib Dhawan et al. J Neuroinflammation. 9:117 (2012) [82]