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Table 4 Disease and drug target association of scaffold protein candidates and kinases

From: Prediction of scaffold proteins based on protein interaction and domain architectures

 

Disease association

Drug target association

 

Scaffold

Kinase

Scaffold

Kinase

Risk ratio

1.26

1.19

1.91

3.94

Odd ratio

1.37

1.27

2.01

4.66

Chi-square value

12.6

5.47

89.12

195.35

p-value

3.85E-04

1.93E-02

2.72E-07

2.16E-44