Skip to main content

Table 4 Representation of ADE information from the literature at different abstraction levels

From: Generalized enrichment analysis improves the detection of adverse drug events from the biomedical literature

Aggregation

ORIGINAL (MeSH terms as extracted from MEDLINE)

LOW (IC 7–10)

MEDIUM (IC 4.5–7)

HIGH (IC 1–5.5)

MeSH 2nd level

# unique candidate ADE pairs

105354

87415

49696

41705

51226

# unique higher-level AE terms

3057

607

156

99

297

# unique AE terms covered

3057

2428

2760

2875

3039

# unique drugs with AE associations

1609

1590

1602

1608

1608

# unique drug classes (ATC 4) with AE associations

565

565

564

565

565