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Table 6 Adverse event signals for drugs detected by GEA and PRR

From: Generalized enrichment analysis improves the detection of adverse drug events from the biomedical literature

p-value

GEA IC 7–10

GEA IC 4.5–6

GEA IC 1–5.5

PRR 2nd

PRR IC 7–10

PRR

<0.1

43702 (22073)

10585 (7634)

12875 (6157)

30547

61108

>1

<0.05

35953 (17140)

9249 (6840)

11453 (5356)

24834

52377

>1.5

<0.005

23059 (10122)

6867 (4931)

8594 (3623)

10810

26953

>5

  1. Adverse event signals for drugs (ATC ingredient names) detected by GEA and PRR using different thresholds at different aggregation levels. The number in bold indicates the unique adverse event association signals found using the optimal configuration (GEA at IC 7–10 with p < 0.005) as determined by the overall performance assessment
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BMC Bioinformatics

ISSN: 1471-2105

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