Prediction of aptamer-protein interacting pairs using an ensemble classifier in combination with various protein sequence attributes

Table 1 Prediction performance of the ensemble RF models using various feature spaces by 10-fold cross validation

Features	Sn	Sp	Acc	MCC	Youden’s index
PseKNC+DCT	0.621	0.641	0.636	0.229	0.261
PseKNC+Bi-gram PSSM	0.660	0.673	0.670	0.293	0.333
PseKNC+Disorder	0.103	0.321	0.267	-0.499	-0.575
PseKNC+DCT+Bi-gram PSSM	0.693	0.666	0.673	0.315	0.359
PseKNC+DCT +Disorder	0.597	0.616	0.611	0.186	0.213
PseKNC+Bi-gram PSSM+Disorder	0.671	0.675	0.674	0.304	0.345
PseKNC+DCT+Bi-gram PSSM+Disorder	0.7	0.680	0.685	0.334	0.380

ISSN: 1471-2105